贝尔法斯特女王大学脑癌科研项目获得资金支持
指南者留学
2023-04-05 15:16:37
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;" data-tools-id="88873">英国女王大学获得北爱尔兰「<strong style="box-sizing: border-box;">Brainwaves NI 机构</strong>」的慷慨捐赠,用于支持大学研究一种叫胶质母细胞瘤癌的脑癌的病因。这笔10万英镑的捐赠将为一名博士生提供为期三年的科研支持,研究失调的 mRNA 翻译如何导致胶质母细胞瘤癌。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Brainwaves NI 机构简介</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">Brainwaves NI 机构是一个位于北爱尔兰的非营利组织,成立于2001年。它的目标是帮助脑损伤或神经系统疾病患者,提供支持、治疗和康复服务,帮助他们在脑损伤后恢复正常的个人和家庭生活,并且提供长期的支持和援助。该组织还通过各种活动和公共宣传来增加社会对脑损伤和神经系统疾病的认识。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">科研挑战</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">胶质母细胞瘤癌是一种可能发生在大脑中的侵袭性癌症。它很难治愈,患者的生存率非常低。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">mRNA 或信使核糖核酸,在将基因组 DNA 中保存的指令转化为我们细胞中的功能性蛋白质方面起着关键作用。mRNA 处理的失调是癌症的标志。相比正常细胞,癌细胞经常出现于异常的 mRNA,这会加速癌症病情和增加癌症治疗抵抗性。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">科研方向</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">Brainwaves NI 组织提供三年资助的科研项目将在英国女王大学 Patrick G Johnston 癌症研究中心的 RNA 生物学实验室开展,研究胶质母细胞瘤癌细胞如何劫持 mRNA 翻译机制,并以此加速胶质母细胞瘤感染情况。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"> Seyed Mehdi Jafarnejad 博士</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"> 英国女王大学 研究员</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">英国女王大学 Seyed Mehdi Jafarnejad 博士是这项研究的首席研究员,他表示:</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">我们很高兴得知 Brainwaves NI 机构对我们的资助,这将为英国女王大学 Patrick G Johnston 癌症研究中心的重要癌症研究提供很大的支持。我们希望通过这个科研项目,能够增加我们对这个经常被忽视的癌症研究领域的重要认识,并最终转化为实践,改善胶质母细胞瘤癌患者的生活。</span></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">Brainwaves NI 组织委员会表示:</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="color: #3e3e3e; box-sizing: border-box;">Brainwaves NI 与英国女王大学 Patrick G Johnston 癌症研究中心有着长期的合作关系</span></strong><span style="color: #3e3e3e; box-sizing: border-box;">,并在过去的6年中提供了共50万英镑的资金支持。这次我们开启了一个科研新方向,并承诺资助一个为期三年的博士研究生项目。寻找治愈脑癌的方法离不开科研,我们很自豪能够资助这个重要的研究项目。 </span></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">抗癌战士 · 英国女王大学</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Patrick G Johnston 癌症研究中心 </strong></p>
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<p style="text-align: center; margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">The Patrick G Johnston Centre</strong></p>
<p style="text-align: center; margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">for Cancer Research</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">Patrick G Johnston 癌症研究中心的使命是通过卓越学术研究,提升对患者的治疗效果,培养下一代科学家和临床医师,并增强英国在生命科学领域的竞争力。PGJ癌症研究中心的研究人员正在领导或参与一系列具有重大国际影响力的研究项目,包括:</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">贝尔法斯特实验癌症医学中心(ECMC)</strong>:由英国癌症研究中心和北爱尔兰公共卫生局(研究与发展部)共同投资,是<span style="color: #d6000d; box-sizing: border-box;"><strong style="box-sizing: border-box;">英国十八大前沿癌症研究中心之一</strong></span></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Movember 前列腺癌研究卓越中心</strong>:<span style="color: #d6000d; box-sizing: border-box;"><strong style="box-sizing: border-box;">英国唯二的前列腺癌研究中心之一</strong></span></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">抗癌科研 优秀成绩单</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">近年来,英国女王大学在抗癌的科研道路上收获硕果累累,以下是其中部分的杰出发展成果。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">01</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">结直肠癌</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">一项由英国女王大学主导参与的研究发现,癌症中的最常见突变基因 p53(也称为“基因组守护者”)可阻止结直肠癌的细胞死亡。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">02</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">癌症和脑部疾病诊断和识别</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">Wellcome-Wolfson 实验医学研究所团队在癌症和脑部疾病诊断和识别方面实现新突破,登上权威学术期刊——《Nature》。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">03</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">乳腺癌</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">药学院的 Niamh Buckley 博士和Helen McCarthy 教授在乳腺癌的治疗方法上获得新突破,获得 Breast Cancer Now 机构研究基金。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">04</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">男性乳腺癌</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">英国女王大学的研究人员联合伦敦癌症研究所(ICR)发现了三种新的基因变化,这些基因变化增加了男性患乳腺癌的风险。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">05</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">血癌</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">英国女王大学和伯明翰大学共同合作的科研小组发现,目前用于治疗某些基因缺陷的癌症药物,也可以用于治疗一种血癌中常见的缺陷基因。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">06</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">肠癌</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">英国女王大学转译癌症基因组学的负责人马克·劳勒教授(Mark Lawler),带领研究团队首次发表里程碑式的研究报告,成功填补了肠癌研究领域的多项空白。</p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">07</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">善用癌症患者数据</strong></p>
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<p style="margin: 0px; padding: 0px; box-sizing: border-box;">英国女王大学数字健康领域的 Mark Lawler 教授参与领导的英国癌症健康数据研究中心「DATA-CAN」提出了癌症数据使用的创新方法,获得英国权威期刊《英国医学杂志》的充分肯定和发表。</p>
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